Assistant Professor
Amsterdam UMC, Netherlands
Joanna E. Klopotowska, PhD PharmD, works as an assistant professor at the Department of Medical Informatics of Amsterdam UMC in The Netherlands. She has over 15 years of experience in healthcare, with various roles such as hospital pharmacist, EHR implementer, medical informatics researcher, and health informatics teacher. Her PharmacoInformatics research line aims to bridge medication safety with medical informatics and focuses on: 1) improvement of pharmacotherapy outcomes in patients with multimorbidity, and 2) improvement of the detection and prevention of adverse drug events. At present, her research focus is on Intensive Care patients and patients with chronic kidney disease. Since patients with multimorbidity are usually excluded from randomized controlled trials, she reuses routinely-collected data from Electronic Health Records (EHRs) to address many existing knowledge gaps regarding the safety and effectiveness of drugs and their combinations. To analyze routinely-collected data, she employs various techniques ranging from conventional statistics to machine learning (ML) and natural language processing (NLP). Specifically, she utilizes methods for causal inference that enable personalized estimations of treatment effects and side effects. To implement real-world pharmacotherapy evidence at the point-of-care, she studies different implementation strategies, including computerized decision support systems, prediction, and causal (ML) models, and audit & feedback dashboards.