Pharmacology

FLUR-ishing: Inhalational Anesthetics in the ICU

Concurrent Session Moderator(s)

• 

  John Devlin, BCCCP, PharmD, MCCM

  Professor
  Northeastern University
  Boston, Massachusetts

Pain, analgesia, and sedation in critically ill patients, particularly those with acute respiratory distress syndrome, is complex. Existing parenteral therapies are associated with significant adverse effects, particularly with respect to hemodynamics and long-term cognitive dysfunction. Volatile anesthetics (e.g., isoflurane, sevoflurane) induce sedation at various levels, especially in difficult-to-sedate patients. A phase III trial is ongoing with possible publication before 2024. Beyond ICU sedation, other indications of interest have emerged with broader use, including treatment of refractory bronchospasm.

Presentations:

• Evidence for or Against the Use of Inhalational Anesthetic Use Outside the OR