Sepsis
Category: One-Hour Concurrent Session
Rethinking Vasopressors: Evolving Evidence and Emerging Concepts in Vasopressor Administration
Patrick Wieruszewski, BCCCP, PharmD
Assistant Professor of Anesthesiology and Pharmacy
Mayo Clinic
Rochester, Minnesota
This session will 1) briefly review the evidence that led Norepinephrine and Vasopressin to become our first and second-line vasopressors of choice, 2) introduce the important emerging concepts of vasopressor-responsiveness and multimodal vasopressor administration (Leone et al. Anaesth Crit Care Pain Med. 2023) and 3) in light of 1 and 2, explore the potential roles of alternative vasopressor agents, particularly catecholamine-sparing vasopressors such as Angiotensin II, in the management of septic shock.